| 摘要: |
| 试验研究了不同质量浓度下(5、20、50 mg/L)三组柴油分散液,对马粪海胆的肠体、性腺、体液三个部位的抗氧化还原系统细胞色素P450活性变化的影响。 结果表明,随着污染暴露时间的增加,三个部位的细胞色素P450活性均呈现出先被诱导、后被抑制的规律,并且油浓度越高,出现诱导和抑制效应的时间越早,活性变化的幅度也越大。海胆P450活性变化在一定程度上能够反映油污染的强度及其对海洋生物的毒性效应,可作为海洋石油烃污染监测的毒理学指标。 |
| 关键词: 油污染 细胞色素P450 马粪海胆(Hemicentrotus pulcherrimus) 毒理效应 |
| DOI： |
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| 基金项目:国家自然科学基金资助项目(40976064, 41276105) |
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| Effect of diesel dispersion on cytochrome P450 activity of Hemicentrotus pulcherrimus |
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| Abstract: |
| In this paper, the effects of different concentrations of diesel(5, 20 and 50 mg/L)on the activities of cytochrome P450 in the intestine, coelomic fluid and gonad of Hemicentrotus pulcherrimus were studied. The results showed that the P450 activities were induced at first and then inhibited with the increase of diesel concentration and exposure time. And the higher the oil concentration is, the earlier the induced and inhibited time occurred, and more significantly the P450 activities changed. Therefore the P450 activity of Hemicentrotus pulcherrimus was a suitable biomarker to mornitor the marine oil pollution since it may somewhat reflect the toxical effects of oil hydrocarbon on marine organisms. |
| Key words: Oil pollution Cytochrome P450 Hemicentrotus pulcherrimus Toxical effects |
