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富含半胱氨酸肠蛋白的研究进展
陈燕^1,2, 孙晨^1,2
1.中国海洋大学海洋生命学院, 山东青岛 266003;2.中国海洋大学海洋生物多样性与进化研究所, 山东青岛 266003

摘要:

富含半胱氨酸肠蛋白是一种含双锌指结构的小分子蛋白，其在锌离子转运、个体发育、免疫防御以及肿瘤发生等多种生理过程中发挥重要作用。作者主要对富含半胱氨酸肠蛋白的结构特点及其在发育和免疫方面的研究进展进行系统概述，并指出其相关作用机制尚待深入研究。

关键词: 富含半胱氨酸肠蛋白 LIM结构域机体发育免疫防御

DOI：10.11759/hykx20200306003

分类号:Q51

基金项目:国家自然科学基金资助项目（31402030）

Research progress of cysteine-rich intestinal protein

CHEN Yan^1,2, SUN Chen^1,2

1.Department of Marine Biology, Ocean University of China, Qingdao 266003, China;2.Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China

Abstract:

Cysteine-rich intestinal protein (CRIP) is a small molecule protein containing a double zinc finger structure. CRIP has been proven to play an important role in zinc ion transport, development, immune defense and tumorigenesis. This min-review primarily focuses on the research progress on development and immune response of CRIP. It also suggests a further study on the mode of CRIP action in development and immunity.

Key words: cysteine-rich intestinal protein LIM domain development immune defense

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