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水产动物源胶原蛋白医学应用研究进展
王明超1,2, 李杰1, 秦松1, 杜振宁2, 李文军1
1.中国科学院 烟台海岸带研究所, 山东 烟台 264005;2.分子药理和药物评价教育部重点实验室 烟台大学, 山东 烟台 264005
摘要:
胶原蛋白具有免疫原性低,生物相容性较好等优点,同时还具有可降解、止血和促进细胞生长增殖的特性。其中水产源胶原蛋白在提取工艺、安全性方面具有更大优势,因此在医学应用方面得到了广泛的研究与应用。本文探讨了水产动物源胶原蛋白在医学应用方面的研究进展,为后续的研究工作提供依据。
关键词:  胶原蛋白  水产动物源  医学应用
DOI:10.11759/hykx20180601001
分类号:Q318.08
基金项目:国家重点研发计划(2018YFD0901102);烟台市创新型海洋医用材料产业孵化聚集创新与示范(YHCX-SW-Y-201701);海洋源功能生物材料及医药制剂开发(KFZD-SW-218);“十三五”海洋经济创新发展示范项目共同资助
Advances and prospects in the research of aquatic collagen for medical applications
WANG Ming-chao1,2, LI Jie1, QIN Song1, DU Zhen-ning2, LI Wen-jun1
1.Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264005, China;2.School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation, Yantai University, Yantai 264005, China
Abstract:
Collagen possesses superior properties, including low immunogenicity, good biocompatibility, biodegradability, hemostasis, and promotion of cell growth. Aquatic collagen has been widely investigated because of its increased safety. This paper explores the progress in the research of aquatic collagen for medical applications and provides a basis for future research work.
Key words:  collagen  aquatic  medical application
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