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大米草中生物活性物质的筛选
徐年军1, 严小军1, 徐继林1, 马红辉1
宁波大学海洋生物工程重点实验室
摘要:
大米草(Spartina anglica)是一种资源丰富的盐沼植物,目前已在中国沿海大量分布,综合开发利用大米草具有重要的生态意义和经济效益。利用硅胶柱层析方法分离大米草甲醇提取物,再分别用DPPH法、纸碟法和MTT法对大米草中40多个组分进行了抗氧化、抗细菌和抗肿瘤活性的筛选。结果得到抗氧化活性组分5个、抗菌活性组分2个、抗肿瘤活性组分3个。目前对其活性先导化合物的分离纯化研究正在进行中。
关键词:  大米草(Spartina anglica)  抗氧化  抗菌  抗肿瘤
DOI:
分类号:
基金项目:宁波市重点博士基金项目(2004A610012)
Screening of bioactive materials in Spartina anglica
Abstract:
Spartina anglica is a common marsh plant along coast of China. Toexplore its ecological and ec onomic values, we screened more than 40 fractions of the extracts were screened by DPPH, paper disc and MTT methods, after S. anglica was methanol extracted of and isolated by silicon column chromatography, for antioxidant, antibacterial and antitumor activities. Results showed that 5 fractions could fight to antioxidant activities, 2 to bacteria, and 3 to tumor cells.
Key words:  Spartina anglica  antioxidant  antibacterial  antitumo
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