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汞、铅对非洲鲫鱼肝线粒体功能影响的初步研究
刘克强¹
中国科学院海洋研究所

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THE EFFECT OF MERCURIC CHLORIDE AND LEAD NITRATE ON THE FUNCTION OF LIVER MITOCHONDRIA OF TILAPIA MOSSAMBICA

Abstract:

Mercuric chloride and lead nitrate were used separately at different concentrations as toxic agent on the liver mitochondria of Tilapia mossambica in vitro. The degree of coupling of oxidative phosphorylation-respiratory control and ADP/0 ratios of the liver mitochondria were examined by oxygen electrode measurements. In cases where sodium succinate was used as substrate, owing to inhibition of 2.5 ppm mercuric chloride on liver mitochondria, RCR and ADP/O ratios decreased markedly.

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