| 摘要: |
| 采用改良的Roberts比较法,观察Mg2+、Fe3+等 金属离子对日本血吸虫毛蚴(Schistosoma japanicum miracidia)的趋向作用及其在"模拟钉螺"中的应用。结果表明,加入1.00mol/L的Mg2+溶液时,日本血吸虫毛蚴在Φ形容器中实验组和对 照组的数目为93:21(P<0.01);Fe3+浓度从0.05mol/L到1.00mol/L变化时,日本血吸虫毛蚴在实验组和对照组的数目分 别是 52:17(P<0.01), 41:7(P<0.01), 225:39(P<0.01), 24:5(P<0.01), 81:29(P<0.01)。 一定配比的明胶混合物释放出的Fe3+离子具有比钉螺处理过的水更强的吸引日本血吸虫毛蚴的能力。Mg2+、Fe3+在适宜的溶液浓度时能够显著影响日本 血吸虫毛蚴的趋向运动,"模拟钉螺"具有比钉螺处理过的水更大的吸引日本血吸虫毛蚴的能力。利用对日本血吸虫毛蚴有趋向作用的物质制成"模拟钉螺"吸引毛 蚴,减少毛蚴侵入钉螺的机会,这种先保护钉螺而最终保护人类的方法有望成为预防日本血吸虫感染的新思路。 |
| 关键词: 日本血吸虫毛蚴(Schistosoma japanicum miracidia) 钉螺 趋向性 |
| DOI： |
| 分类号: |
| 基金项目: |
|
| A preliminary observation of the materials attracting Schistosoma japanicum miracidia |
|
|
| Abstract: |
| With the improved Roberts testing technique, after adding 1.00 mol/L of Mg2+ to the test side of the ф-shape container, the number of Schistosoma japanicum miracidia in the two separated areas is 93:21(P<0.01), while the concentration of Fe3+ changes from 0.05mol/L to 1.00mol/L, the numbers of S. japanicum miracidia in the two separated areas are 81:29(P<0.01), 24:5(P<0.01), 225:39(P<0.01), 41:7 (P<0.01), and 52:17(P<0.01), respectively. Fe3+ released from the mixture of gelatin and FeCl3 has a stronger affinity to miracidias than the SCW. Mg2+, Fe3+ can affect the chemotaxis of S. japanicum miracidia, and the artificial oncomelania, made with a proper ratio of attractive ions and organic materials, shows an even stronger attraction to S. japanicum miracidias than miraxone released by oncomelania. |
| Key words: Schistosoma japanicum miracidia snail oncomelania chemotaxis |
