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草鱼出血病病毒的研究进展
李军, 王铁辉, 陆仁后, 陈宏溪
中国科学院水生生物研究所 武汉430072
摘要:
根据80－90年代中国关于草鱼出血病病毒研究的进展，就草鱼出血病病毒的发现、形态结构特征、理化特性、基因组结构及其所编码的多肽、基因组的转录和翻译过程，病毒的繁殖动态、体外细胞培养特性，病毒对鱼体的致病机理和宿主范围，草鱼出血病的诊断和防治等问题进行综合评述，总结概括了草鱼出血病病毒的研究现状以及研究中需要亟待解决的问题，并提出该领域以后的重点研究方向。
关键词:  草鱼出血病病毒  水生动物呼肠孤病毒  研究进展
DOI：
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基金项目:国家“八五”攻关课题，857220902号
ADVANCES IN RESEARCH OF HEMORRHAGIC VIRUS OF GRASS CARP
LI Jun, WANG Tie-hui, LU Ren－hou, CHEN Hong-xi
Institute of Hydrobiology, The Chinese Academy of Sciences, Wuhan, 430072
Abstract:
In the 1980's and 1990's progress has been made in the research of grass carp of hemorrhagic virus (GCHV) in China. The most important deviances about GCHV included: 1) the discovery of GCHV; 2) the morphological, biochemical and ultrastructural characteristics; 3) the characteristics of its genome and encoded peptides; 4) the control ling mechanism of genomic transcription and following translation of the GCHV; 5) the characteristics of viral proliferation in vivo and in vitro; 6) the host range and corresponding pathogenesis; and 7) the current strategies on diagnosis and control of GCHV.
Key words:  Grass carp hemorrhagic virus (GCHV), Aquareovirus, Research advance
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