| 摘要: |
| 分别采用MTT法、双碟法、酶标法、光度法和增重法测定了广西涠洲岛、广东硇洲岛、山东青岛和威海沿岸具有代表性的大型海藻提取物的抗肿瘤、抗菌、免疫、抗炎、抑制A-葡萄糖苷酶和抗氧化的活性。结果表明, 鸭毛藻、松节藻、小粘膜藻和点叶藻的甲醇提取物具有选择性细胞毒活性;酸藻水相、鸭毛藻的乙酸乙酯相有较强的抗菌活性; 金膜藻、网地藻、石莼和萱藻的甲醇提取物有较好的免疫抑制活性; 三叉仙菜、龙须菜、海萝、绳藻和小粘膜藻的甲醇提取物有较好的免疫增强活性; 细枝软骨藻、粗枝软骨藻和绳藻的甲醇提取物有显著的抗炎活性; 松节藻、肠浒苔和扁江蓠的脂溶性提取物能有效地抑制A-葡萄糖苷酶的活性; 褐藻多酚具有明显的抗氧化活性。 |
| 关键词: 海藻, 提取物, 活性 |
| DOI： |
| 分类号: |
| 基金项目:国家自然科学重点基金资助项目, B20001702号 |
附件 |
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| STUDY ON BIOACTIVITY OF CHINESE MARINE ALGA EXTRACTS |
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XU Xiu-Li1,2,1, FAN Xiao1,2,1, SONG Fu-Hang1,2,1
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1.Institute of Oceanology , Chinese Academy of Sciences;2.Graduate school of the Chinese Academy of Sciences
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| Abstract: |
| The extracts of 27 red alga, 27 brown alga and 8 green alga, which were collected from the coasts of Weizhou island off Guangxi Province, Naozhou island off Guangdong Province, Qingdao and Weihai in Shandong Province, were tested for anti-tumor, antibacterial, immunity, anti-inflammatory activity and the inhibitory effect against alpha-glucosidase. Of the marine alga tested, methanol extracts ofSymphyocladia latiuscula, Rhodomela conf ervoides, Leathesia nana and Punctaria latif olia showed marked selective cytotoxic activity; water portion of Desmarestia viridis and acetic ether portion of Symphyocladia latiuscula showed high antibacterial activity; methanol extracts of Chrysymenia wrightii , Dictyota dichotoma, Scytosiphon lomentarius and Ulva lactuca showed strong immune inhibitory activity, Ceramium kondoi , Gracilaria lemaneif ormis, Gloiopeltis furcata, Chorda f ilum and Leathesia nana have strong immune enhancement activity; methanol extracts of Chondria tenuissima, Chondria crasscaulis and Chordaf ilum showed notable anti-inflammatory activity; lipophilic extracts of Rhodomela confervoides, Enteromorpha intestinalis and Gracilaria textorii remarkably inhibited alpha-glucosidase activity; polyphenols from brown alga could effectively prevent fish oil from being oxidized. |
| Key words: Marine alga, Extract, Activity |
