| 摘要: |
| 贝类对全球渔业发展和人类生计至关重要,其产量约占世界海水养殖产量的56%。雌雄同体型Argopecten属海湾扇贝(Argopecten irradians irradians)和紫扇贝(Argopecten purpuratus)是具有高营养价值和经济价值的贝类,二者的种间杂交后代表现出极显著的生长优势,具有巨大的育种潜力。然而,两者的绝大多数杂交后代都表现为不育,限制了杂交育种技术的进一步开发和规模化应用。本文从遗传和环境角度综述了两种Argopecten属扇贝种间杂交不育的潜在机制。线粒体基因和核基因突变、异常核质相互作用、表观遗传修饰失调以及环境因子温度变化引起的能量供应不足、有丝分裂和减数分裂缺陷、高水平的细胞凋亡和活性氧水平以及配子的发生和成熟受阻可能是导致Argopecten属扇贝种间杂交不育的关键原因。此外,EGFR基因也在杂交贝的育性调控中发挥着重要的作用。本综述为揭示扇贝种间杂交不育的决定机制提供了新的策略和方向,并为贝类的规模化杂交育种奠定了理论基础,有望为相关研究提供参考以促进水产养殖业的健康发展。 |
| 关键词: 杂交不育 雌雄同体 Argopecten属扇贝 细胞凋亡 能量缺陷 减数分裂 |
| DOI：10.11759/hykx20241008001 |
| 分类号:P735 |
| 基金项目:国家自然科学基金项目(31972791,42276147);山东省重点研发计划项目(2023ZGCQY006);山东省贝类产业技术体系遗传育种岗位专家(SDAIT-14) |
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| Mechanisms determining interspecific hybrid sterility in Argopecten scallops |
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YU Tieying1,2, NING Junhao1,2, LU Xia3, WANG Chunde1,2
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1.Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China;2.University of Chinese Academy of Sciences, Beijing 100049, China;3.Yantai University, Yantai 264005, China
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| Abstract: |
| Molluscs are vital to the global fishery industry and livelihood, accounting for approximately 56% of the world’s mariculture production. The hermaphroditic bay scallop (Argopecten irradians irradians) and Peruvian scallop (Argopecten purpuratus) are shellfish with high nutritional and economic value. The interspecific hybrids between the two exhibit remarkable advantages in growth, with Argopecten breeding possessing great potential. Nevertheless, most hybrids are infertile, limiting further development and the large-scale application of scallop crossbreeding technology. This review summarizes the potential mechanisms underlying such sterility from genetic and environmental perspectives. Insufficient energy supply, dysregulation of mitosis and meiosis, elevated levels of reactive oxygen species (ROS) and apoptosis, obstruction of gametogenesis and maturation due to mutated mitochondrial and nuclear genes, aberrant nucleocytoplasmic interactions, defective epigenetic modifications, and changes in the environmental temperature may be the most critical reasons. Besides, EGFR may also play a key role in regulating fertility in hybrid scallops. This review may provide new insights into understanding the mechanisms determining interspecific hybrid sterility in scallops and lay a theoretical foundation for the large-scale hybrid breeding of shellfish. It is expected to provide related references to promote the healthy development of the aquaculture industry. |
| Key words: hybrid sterility hermaphroditic Argopecten scallops apoptosis energy deficiency meiosis |
